Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits
- Creator: Keaton, Jacob M. , Kamali, Zoha , Young, William J. , Lehtimäki, T , Raitakari, OT , Johnson, AD , Newton-Cheh, C , Brown, MJ , Dominiczak, AF , Sever, PJ , Poulter, N , Chambers, JC , Elosua, R , Traylor, Matthew , Siscovick, D , Esko, T , Metspalu, A , Strawbridge, RJ , Laakso, M , Hamsten, A , Hottenga, J-J , de Geus, E , Morris, AD , Palmer, CNA , Giri, Ayush , Nolte, IM , Milaneschi, Y , Marten, J , Wright, A , Zeggini, E , Howson, JMM , O'Donnell, CJ , Spector, T , Nalls, MA , Simonsick, EM , Zheng, Zhili , Liu, Y , van Duijn, CM , Butterworth, AS , Danesh, JN , Menni, C , Wareham, NJ , Khaw, K-T , Sun, YV , Wilson, PWF , Cho, K , Zeng, Jian , Visscher, PM , Denny, JC , Million Veteran Program, , Lifelines Cohort Study, , CHARGE consortium, , ICBP Consortium, , Levy, D , Edwards, TL , Munroe, PB , Snieder, H , Chasman, Daniel I. , Warren, HR , Morris, Andrew P. , Caulfield, Mark J. , Hwang, Shih-Jen , Kooner, Jaspal S. , Xie, Tian , Attia, John R. , Attia, JR , Morrison, AC , Loos, RJF , Kristiansson, K , Schmidt, R , Hicks, AA , Pramstaller, PP , Nelson, CP , Samani, NJ , Vaez, Ahmad , Risch, L , Gyllensten, U , Melander, O , Riese, H , Wilson, JF , Campbell, H , Rich, SS , Psaty, BM , Lu, Y , Rotter, JI , Williams, Ariel , Guo, X , Rice, KM , Vollenweider, P , Sundström, J , Langenberg, C , Tobin, MD , Giedraitis, V , Luan, J , Tuomilehto, J , Kutalik, Z , Goleva, Slavina B. , Ripatti, S , Salomaa, V , Girotto, G , Trompet, S , Jukema, JW , van der Harst, P , Ridker, PM , Giulianini, F , Vitart, V , Goel, A , Ani, Alireza , Watkins, H , Harris, SE , Deary, IJ , van der Most, PJ , Oldehinkel, AJ , Keavney, BD , Hayward, C , Campbell, A , Boehnke, M , Scott, LJ , Evangelou, Evangelos , Boutin, T , Mamasoula, C , Järvelin, M-R , Peters, A , Gieger, C , Lakatta, EG , Cucca, F , Hui, J , Knekt, P , Enroth, S , Hellwege, Jacklyn N. , De Borst, MH , Polašek, O , Concas, MP , Catamo, E , Cocca, M , Li-Gao, R , Hofer, E , Schmidt, H , Spedicati, B , Waldenberger, M , Yengo, Loic , Strachan, DP , Laan, M , Teumer, A , Dörr, M , Gudnason, V , Cook, JP , Ruggiero, D , Kolcic, I , Boerwinkle, E , Traglia, M
- Resource Type: journal article
- Date: 2024
Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease
- Creator: Crawford, Andrew A. , Bankier, Sean , Lahti, Jari , Mahajan, Anubha , Mangino, Massimo , Nethander, Maria , Neumann, Alexander , Pietzner, Maik , Sukhavasi, Katyayani , Wang, Carol A. , Bakker, Stephan J. L. , Bjorkegren, Johan L. M. , Altmaier, Elisabeth , Campbell, Harry , Eriksson, Johan , Gieger, Christian , Hayward, Caroline , Jarvelin, Marjo-Riitta , McLachlan, Stela , Morris, Andrew P. , Ohlsson, Claes , Pennell, Craig E. , Price, Jackie , Barnes, Catriona L. K. , Rudan, Igor , Ruusalepp, Arno , Spector, Tim , Tiemeier, Henning , Volzke, Henry , Wilson, James F. , Michoel, Tom , Timpson, Nicolas J. , Smith, George Davey , Walker, Brian R. , Clark, David W. , Ermel, Raili , Friedrich, Nele , van der Harst, Pim , Joshi, Peter K. , Karhunen, Ville
- Resource Type: journal article
- Date: 2021
Genetic overlap between endometriosis and endometrial cancer: Evidence from cross-disease genetic correlation and GWAS meta-analyses
- Creator: Painter, Jodie N. , O'Mara, Tracy A. , Henders, Anjali K. , Attia, John , McEvoy, Mark , Holliday, Elizabeth G. , Scott, Rodney J. , Webb, Penelope M. , Fasching, Peter A. , Beckmann, Matthias W. , Ekici, Arif B. , Hein, Alexander , Morris, Andrew P. , Rübner, Matthias , Hall, P , Czene, K , Dörk, T , Dürst, M , Hillemanns, P , Runnebaum, I , Lambrechts, D , Amant, F , Annibali, D , Cheng, Timothy H. T. , Depreeuw, J , Vanderstichele, A , Goode, EL , Cunningham, JM , Dowdy, SC , Winham, SJ , Trovik, J , Hoivik, E , Werner, HMJ , Krakstad, C , Gorman, Maggie , Ashton, Katie , Otton, Geoffrey , Proietto, Tony , Tham, E , Mints, M , Ahmed, S , Healey, CS , Shah, M , Pharoah, PDP , Dunning, AM , Martin, Lynn , Dennis, J , Bolla, MK , Michailidou, K , Wang, Q , Tyrer, JP , Hopper, JL , Peto, J , Swerdlow, AJ , Burwinkel, B , Brenner, H , Hodson, Shirley , Meindl, A , Brauch, H , Lindblom, A , Chang-Claude, J , Couch, FJ , Giles, GG , Kristensen, VN , Cox, A , Zondervan, KT , Nyholt, DR , Jones, Angela , Macgregor, S , Montgomery, GW , Martin, Nnicholas G. , Gordon, Scott
- Resource Type: journal article
- Date: 2018
Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium mendelian randomization study
- Creator: Prins, Bram P. , Abbasi, Ali , Valdes, Ana M. , Bras, Jose , Shatunov, Aleksey , Lu, Chen , Han, Buhm , Raychaudhuri, Soumya , Bevan, Steve , Mayes, Maureen D. , Tsoi, Lam C. , Evangelou, Evangelos , Wong, Anson , Nair, Rajan P. , Grant, Stuan F. A. , Polychronakos, Constantin , Radstake, Timothy R. D. , van Heel, David A. , Dunstan, Melanie L. , Wood, Nicholas W. , Al-Chalabi, Ammar , Dehghan, Abbas , Hakonarson, Hakon , Vaez, Ahmad , Markus, Hugh S. , Elder, James T. , Knight, Jo , Arking, Dan E. , Spector, Timothy D. , Koeleman, Bobby P. C. , van Duijn, Cornelia M. , Martin, Javier , Morris, Andrew P. , Weersma, Rinse K. , Nolte, Ilja , Wijmenga, Cisca , Munroe, Patricia B. , Perry, John R. B. , Pouget, Jennie G. , Jamshidi, Yalda , Snieder, Harold , Alizadeh, Behrooz Z. , Tooney, Paul , Franceschini, Nora , Stuart, Philip E. , Guterriez Achury, Javier , Mistry, Vanisha , Bradfield, Jonathan P.
- Resource Type: journal article
- Date: 2016
Association between endometriosis and the interleukin 1A (IL1A) locus
- Creator: Sapkota, Yadav , Low, Siew-Kee , Takahashi, Atsushi , Scott, Rodney J. , Kubo, Michiaki , Zondervan, Krina T. , Montgomery, Grant W. , Nyholt, Dale R. , Attia, John , Gordon, Scott D. , Henders, Anjali K. , Holliday, Elizabeth G. , MacGregor, Stuart , Martin, Nicholas G. , McEvoy, Mark , Morris, Andrew P.
- Resource Type: journal article
- Date: 2015
Genetic burden associated with varying degrees of disease severity in endometriosis
- Creator: Sapkota, Yadav , Attia, John , Scott, Rodney J. , Zondervan, Krina T. , Montgomery, Grant W. , Nyholt, Dale R. , Gordon, Scott D. , Henders, Anjali K. , Holliday, Elizabeth G. , Rahmioglu, Nilufer , MacGregor, Stuart , Martin, Nicholas G. , McEvoy, Mark , Morris, Andrew P.
- Resource Type: journal article
- Date: 2015
Genome-wide association analysis identifies six new loci associated with forced vital capacity
- Creator: Loth, Daan W. , Artigas, María Soler , Lee, Mi Kyeong , Scott, Rodney J. , Karrasch, Stefan , Grallert, Harald , Gaddis, Nathan C. , Starr, John M. , Wijmenga, Cisca , Minster, Ryan L. , Lederer, David J. , Pekkanen, Juha , Gyllensten, Ulf , Strachan, David P. , Campbell, Harry , Morris, Andrew P. , Gläeser, Sven , Hammond, Christopher J. , Burkart, Kristin M. , Beilby, John , Kritchevsky, Stephen B. , Gucinason, Vilmundur , Hancock, Dana B. , Williams, O. Dale , James, Alan L. , Polasek, Ozren , Zemunik, Tatijana , Kolcic, Ivana , Petrini, Marcy F. , Wjst, Matthias , Kim, Woo Jin , Porteous, David J. , Scotland, Generation , Smith, Blair H. , Viljanen, Anne , Huffman, Jennifer E. , Heliovaara, Markku , Attia, John R. , Sayers, Ian , Hampel, Regina , Gieger, Christian , Deary, Ian J. , Boezen, H. Marike , Newman, Anne , Jarvelin, Marjo-Riitta , Wilson, James F. , Vitart, Veronique , Lind, Lars , Stricker, Bruno H. , Teumer, Alexander , Spector, Timothy D. , Melén, Erik , Peters, Marjolein J. , Lange, Leslie A. , Barr, R. Graham , Bracke, Ken R. , Verhamme, Fien M. , Ramasamy, Adaikalavan , Sung, Joohon , Hiemstra, Pieter S. , Cassano, Patricia A. , Sood, Akshay , Hayward, Caroline , Dupuis, Josée , Hall, Ian P. , Brusselle, Guy G. , Tobin, Martin D. , London, Stephanie J. , Wareham, Nicholas J. , Kaprio, Jaakko , Wang, Xin-Qun , Trochet, Holly , Gharib, Sina A. , Kähönen, Mika , Flexeder, Claudia , Albrecht, Eva , Lopez, Lorna M. , de Jong, Kim , Thyagarajan, Bharat , Alves, Alexessander Couto , Enroth, Stefan , Omenaas, Ernst , Joshi, Peter K. , Wain, Louise V. , Fall, Tove , Viñuela, Ana , Launer, Lenore J. , Loehr, Laura R. , Fornage, Myriam , Li, Guo , Wik, Jemma B. , Tang, Wenbo , Manichaikul, Ani , Lahousse, Lies , Franceschini, Nora , Harris, Tamara B. , North, Kari E. , Rudnicka, Alicja R. , Hui, Jennie , Gu, Xiangjun , Lumley, Thomas , Wright, Alan F. , Hastie, Nicholas D. , Campbell, Susan , Kumar, Rajesh , Koch, Beate , Pin, Isabelle , Scott, Robert A. , Pietilainen, Kirsi H. , Surakka, Ida , Liu, Yongmei , Holliday, Elizabeth G. , Schulz, Holger , Heinrich, Joachim , Davies, Gail , Vonk, Judith M. , Pottinger, Tess D. , Wojczynski, Mary , Pouta, Anneli , Johansson, Åsa , Wild, Sarah H. , Ingelsson, Erik , Rivadeneira, Fernando , Vöezke, Henry , Hysi, Pirro G. , Eiriksdottir, Gudny , Morrison, Alanna C. , Smith, Albert Vernon , Rotter, Jerome I. , Gao, Wei , Postma, Dirkje S. , White, Wendy B. , Rich, Stephen S. , Hofman, Albert , Aspelund, Thor , Couper, David , Smith, Lewis J. , Psaty, Bruce M. , Duan, Qing , Lohman, Kurt , Burchard, Esteban G. , Uitterlinden, André G. , Garcia, Melissa , Joubert, Bonnie R. , McArdle, Wendy L. , Musk, A. Bill , Hansel, Nadia , Heckbert, Susan R. , Zgaga, Lina , Oldmeadow, Chris , van Meurs, Joyce B. J. , Navarro, Pau , Rudan, Igor , Oh, Yeon-Mok , Redline, Susan , Jarvis, Deborah L. , Zhao, Jing Hua , Rantanen, Taina , O'Connor, George T. , Ripatti, Samuli
- Resource Type: journal article
- Date: 2014
Genome-wide association meta-analysis identifies new endometriosis risk loci
- Creator: Nyholt, Dale R. , Low, Siew-Kee , Attia, John , Holliday, Elizabeth G. , McEvoy, Mark , Scott, Rodney J. , Kennedy, Stephen H. , Treloar, Susan A. , Missmer, Stacey A. , Adachi, Sosuke , Tanaka, Knichi , Nakamura, Yusuke , Anderson, Carl A. , Zondervan, Krina T. , Zembutsu, Hitoshi , Montgomery, Grant W. , Painter Jodie N., Yun-Chul , Uno, Satoko , Morris, Andrew P. , MacGregor, Stuart , Gordon, Scott D. , Henders, Anjali K. , Martin, Nicholas G.
- Resource Type: journal article
- Date: 2012